BACKGROUND: The aim of this study was to investigate whether electromyographic manifestations of fatigue and exercise tolerance were related to stage of disease in men with a COPD diagnosis.METHODS: Fourteen men with COPD with a diagnosis of mild to severe air flow obstruction were involved in 2 separate testing sessions. The first one consisted of a pulmonary function (FEV1 and FEV1/FVC) and an exercise tolerance assessment using the 6-min walk test. During the second session, a multichannel surface electromyography was recorded from vastus medialis and vastus lateralis muscles during an isometric knee extension at 70% of maximum voluntary contraction. The slope of muscle fiber conduction velocity during the contraction was calculated as the index of fatigue. RESULTS: Conduction velocity slope significantly correlated with FEV1 (vastus medialis: r = 0.86, P < .001; vastus lateralis: r = 0.68, P = .01), FEV1/FVC (vastus medialis: r = 0.70, P = .006), and 6-min walk test (vastus medialis: r = 0.72, P = .005; vastus lateralis: r = 0.80, P = .001).CONCLUSIONS: The electromyographic manifestations of fatigue during sustained quadriceps contraction significantly correlated with disease severity and exercise tolerance in moderate to severe COPD.

Electromyographic manifestations of fatigue correlate with pulmonary function, 6-minute walk test, and time to exhaustion in COPD

BOCCIA, GENNARO;RINALDO, Nicoletta;CORATELLA, Giuseppe;SCHENA, Federico;
2015-01-01

Abstract

BACKGROUND: The aim of this study was to investigate whether electromyographic manifestations of fatigue and exercise tolerance were related to stage of disease in men with a COPD diagnosis.METHODS: Fourteen men with COPD with a diagnosis of mild to severe air flow obstruction were involved in 2 separate testing sessions. The first one consisted of a pulmonary function (FEV1 and FEV1/FVC) and an exercise tolerance assessment using the 6-min walk test. During the second session, a multichannel surface electromyography was recorded from vastus medialis and vastus lateralis muscles during an isometric knee extension at 70% of maximum voluntary contraction. The slope of muscle fiber conduction velocity during the contraction was calculated as the index of fatigue. RESULTS: Conduction velocity slope significantly correlated with FEV1 (vastus medialis: r = 0.86, P < .001; vastus lateralis: r = 0.68, P = .01), FEV1/FVC (vastus medialis: r = 0.70, P = .006), and 6-min walk test (vastus medialis: r = 0.72, P = .005; vastus lateralis: r = 0.80, P = .001).CONCLUSIONS: The electromyographic manifestations of fatigue during sustained quadriceps contraction significantly correlated with disease severity and exercise tolerance in moderate to severe COPD.
6-minute walk test; COPD; electromyography; muscle endurance; neuromuscular fatigue; vastus lateralis; vastus medialis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/929154
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