Different strategies have been proposed to target neoangiogenesis in gliomas, besides those targeting Vascular Endothelial Growth Factor (VEGF). The chemokine Interleukin-8 (IL-8) has been shown to possess both tumorigenic and proangiogenic properties. Although different pathways of induction of IL-8 gene expression have been already elucidated, few data are available on its post-transcriptional regulation in gliomas.

Regulation of IL-8 gene expression in gliomas by microRNA miR-93

GHIMENTON, CLAUDIO;ECCHER, Albino;CANTÙ, Cinzia;BEZZERRI, Valentino;PROVEZZA, Lisa;MORETTO, Giuseppe;CHILOSI, Marco;CABRINI, GIULIO;
2015-01-01

Abstract

Different strategies have been proposed to target neoangiogenesis in gliomas, besides those targeting Vascular Endothelial Growth Factor (VEGF). The chemokine Interleukin-8 (IL-8) has been shown to possess both tumorigenic and proangiogenic properties. Although different pathways of induction of IL-8 gene expression have been already elucidated, few data are available on its post-transcriptional regulation in gliomas.
2015
gliomas , chemokine Interleukin-8 (IL-8), miR-93
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/928276
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