8-Hydroxydeoxyguanosine (8-OHdG) is a commonly used marker of DNA oxidative stress in epidemiological studies. The aim of this study was to establish whether the urinary concentration of 8-OHdG varies during the first part of the day, when clinical tests are usually performed, and whether it can therefore be measured without bias in spot urine samples.

Measurement of a urinary marker (8-hydroxydeoxy-guanosine, 8-OHdG) of DNA oxidative stress in epidemiological surveys: a pilot study

Zanolin, Maria Elisabetta;Girardi, Paolo;Rava, Marta;Olivieri, Mario;DI GENNARO, Gianfranco;Nicolis, Morena;DE MARCO, Roberto
2015-01-01

Abstract

8-Hydroxydeoxyguanosine (8-OHdG) is a commonly used marker of DNA oxidative stress in epidemiological studies. The aim of this study was to establish whether the urinary concentration of 8-OHdG varies during the first part of the day, when clinical tests are usually performed, and whether it can therefore be measured without bias in spot urine samples.
8-Hydroxy-2´-deoxyguanosine; Biomarkers; DNA oxidation; Epidemiology; Oxidative damage; Oxidative stress
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/927207
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