Antiplatelet activity of β-blockers: new light on existing data

Comment onEffect of β-blockers on platelet aggregation: a systematic review and meta-analysis. [Br J Clin Pharmacol. 2014]

Extensive evidence of cardiovascular protectionwith β-blockers has been obtained from large-scalerandomized clinical trials and meta-analyses. However,limited information is available from head-to-head com-parisons of new and old compounds concerning majorcardiovascular events. Heterogeneity among individualcompounds appears evident. The evidence of anantiplatelet activity endowed in some β-blockers needs tobe substantiated by further clinical investigation.