Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor and uncoupler of nitric oxide synthase. By promoting the formation of peroxynitrite, ADMA is believed to contribute to several aspects of asthma pathogenesis (ie, airway inflammation, oxidative stress, bronchial hyperresponsiveness, and collagen deposition). The aim of the present study was to compare this mediator in healthy children and children with asthma using the completely noninvasive exhaled breath condensate (EBC) technique.

ASYMMETRIC DIMETHYLARGININE (ADMA) IN EXHALED BREATH CONDENSATE AND SERUM OF ASTHMATIC CHILDREN.

PIACENTINI, Giorgio;Moser, Serena;
2013-01-01

Abstract

Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor and uncoupler of nitric oxide synthase. By promoting the formation of peroxynitrite, ADMA is believed to contribute to several aspects of asthma pathogenesis (ie, airway inflammation, oxidative stress, bronchial hyperresponsiveness, and collagen deposition). The aim of the present study was to compare this mediator in healthy children and children with asthma using the completely noninvasive exhaled breath condensate (EBC) technique.
2013
Asymmetric dimethylarginine; asthma; exhaled breath condensate (EBC)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/713562
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