The cerebellum has been shown to be a region highly subject to demyelination1-4 and compensatory plasticity5 in late multiple sclerosis (MS). However, its involvement in the early phases of the disease is still poorly understood. The aim of this study was to determine if connectivity changes are observable in the cerebellum of early and minimally impaired MS patients and if they can be correlated to the patient’s clinical performances.
Cerebellar connectomics provide new biomarkers in early multiple sclerosis
Lin, YING CHIA;MENEGAZ, Gloria;DADUCCI, Alessandro;
2014-01-01
Abstract
The cerebellum has been shown to be a region highly subject to demyelination1-4 and compensatory plasticity5 in late multiple sclerosis (MS). However, its involvement in the early phases of the disease is still poorly understood. The aim of this study was to determine if connectivity changes are observable in the cerebellum of early and minimally impaired MS patients and if they can be correlated to the patient’s clinical performances.
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