Potassium-enriched depolarizing arrest (DA) is still the worldwide accepted method for myocardial protection. Despite animal models have demonstrated superior protection with no-potassium polarizing arrest (PA), and clinical studies reported lower perioperative myocardial enzymatic release, intra-cellular effects of PA vs DA in human myocardial specimens are still ill-defined.

Effects of polarizing microplegia vs standard high-potassium depolarizing microplegia on intracellular metabolism, pro-survival kinases, and apoptosis in humans.

Gandhi, Kushal Yogeshchandra;RUNGATSCHER, Alessio;TESSARI, Maddalena;LINARDI, Daniele;ONORATI, FRANCESCO;MAZZUCCO, Alessandro;FAGGIAN, Giuseppe
2014

Abstract

Potassium-enriched depolarizing arrest (DA) is still the worldwide accepted method for myocardial protection. Despite animal models have demonstrated superior protection with no-potassium polarizing arrest (PA), and clinical studies reported lower perioperative myocardial enzymatic release, intra-cellular effects of PA vs DA in human myocardial specimens are still ill-defined.
Potassium-enriched depolarizing arrest; myocardial protection; no-potassium polarizing arrest; human myocardial
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/662971
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact