Potassium-enriched depolarizing arrest (DA) is still the worldwide accepted method for myocardial protection. Despite animal models have demonstrated superior protection with no-potassium polarizing arrest (PA), and clinical studies reported lower perioperative myocardial enzymatic release, intra-cellular effects of PA vs DA in human myocardial specimens are still ill-defined.

Effects of polarizing microplegia vs standard high-potassium depolarizing microplegia on intracellular metabolism, pro-survival kinases, and apoptosis in humans.

Gandhi, Kushal Yogeshchandra;RUNGATSCHER, Alessio;TESSARI, Maddalena;LINARDI, Daniele;ONORATI, FRANCESCO;MAZZUCCO, Alessandro;FAGGIAN, Giuseppe
2014-01-01

Abstract

Potassium-enriched depolarizing arrest (DA) is still the worldwide accepted method for myocardial protection. Despite animal models have demonstrated superior protection with no-potassium polarizing arrest (PA), and clinical studies reported lower perioperative myocardial enzymatic release, intra-cellular effects of PA vs DA in human myocardial specimens are still ill-defined.
2014
Potassium-enriched depolarizing arrest; myocardial protection; no-potassium polarizing arrest; human myocardial
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/662971
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