IL-6 and CCL5 are implicated in the development and progression of several forms of tumours incliding PCa. The PSMA expression is augmented in high-grade and metastatic tumours. Some clinical observations suggest that the increased secretion of IL-6 and CCL5 and the higher PSMA expression may be correlated.
The prostate specific membrane antigen regulates the expression of IL-6 and CCL-5 in prostate tumour cells by activating the MAPK pathways
COLOMBATTI, Marco;GRASSO, Silvia;FRACASSO, Giulio;SCUPOLI, Maria;CINGARLINI, Sara;RAMARLI, DUNIA
2009-01-01
Abstract
IL-6 and CCL5 are implicated in the development and progression of several forms of tumours incliding PCa. The PSMA expression is augmented in high-grade and metastatic tumours. Some clinical observations suggest that the increased secretion of IL-6 and CCL5 and the higher PSMA expression may be correlated.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
