IL-6 and CCL5 are implicated in the development and progression of several forms of tumours incliding PCa. The PSMA expression is augmented in high-grade and metastatic tumours. Some clinical observations suggest that the increased secretion of IL-6 and CCL5 and the higher PSMA expression may be correlated.

The prostate specific membrane antigen regulates the expression of IL-6 and CCL-5 in prostate tumour cells by activating the MAPK pathways

COLOMBATTI, Marco;GRASSO, Silvia;FRACASSO, Giulio;SCUPOLI, Maria;CINGARLINI, Sara;RAMARLI, DUNIA
2009

Abstract

IL-6 and CCL5 are implicated in the development and progression of several forms of tumours incliding PCa. The PSMA expression is augmented in high-grade and metastatic tumours. Some clinical observations suggest that the increased secretion of IL-6 and CCL5 and the higher PSMA expression may be correlated.
Prostate Specific Membrane Antigen (PSMA); IL-6; CCL-5; prostate cancer
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/617752
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