PSMA is an integral membrane glycoprotein that is overexpressed in prostate carcinomas rendering this cell surface marker an appropriate target for antibody-vehicled drugs and toxins. We have investigated PSMA biosynthesis, O and N-glycosylation, transport and association with lipid microdomains.

Prostate-specific membrane antigen associates already in the endoplasmic reticulum with lipid microdomains

CASTELLETTI, Deborah;FRACASSO, Giulio;COLOMBATTI, Marco;
2004

Abstract

PSMA is an integral membrane glycoprotein that is overexpressed in prostate carcinomas rendering this cell surface marker an appropriate target for antibody-vehicled drugs and toxins. We have investigated PSMA biosynthesis, O and N-glycosylation, transport and association with lipid microdomains.
Prostate Specific Membrane Antigen (PSMA); lipid microdomains; prostate cancer
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/617751
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