PSMA is an integral membrane glycoprotein that is overexpressed in prostate carcinomas rendering this cell surface marker an appropriate target for antibody-vehicled drugs and toxins. We have investigated PSMA biosynthesis, O and N-glycosylation, transport and association with lipid microdomains.
Titolo: | Prostate-specific membrane antigen associates already in the endoplasmic reticulum with lipid microdomains | |
Autori: | ||
Data di pubblicazione: | 2004 | |
Rivista: | ||
Abstract: | PSMA is an integral membrane glycoprotein that is overexpressed in prostate carcinomas rendering this cell surface marker an appropriate target for antibody-vehicled drugs and toxins. We have investigated PSMA biosynthesis, O and N-glycosylation, transport and association with lipid microdomains. | |
Handle: | http://hdl.handle.net/11562/617751 | |
Appare nelle tipologie: | 01.05 Abstract in rivista |
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