We have analyzed the association between sexuaUy transmitted diseases (STO) and HIV infection, using data from a crosssectionaI survey of subjects attending STO cIinics in Northern ItaIy conducted since 1988. A totaI of 1,711 subjects (1,259 maIes, 452 females), who had referred themseIves to three STO cIinics in Northern Italy for suspected STO or STO treatment, were included for the study. Out of these, 145 subjects (113 males and 32 females) were Hlv-positìve. A total of 58 mv -positive and 368 mv -negative subjects reported a history of STO; the corresponding odds ratio (OR) was 2.3 (95% confidence interval (CI) 1.5-3.6) for subjects reporting a bistory of STO. Considering various STD in detaiIs, tbe estimated OR was 1.8 (95"1. CI 0.8-3.8) for a bistory of gonorrboea and 1.5 (95% CI 0.8-2.7) of syphilis, and tbe OR was 1.8 (95% CI 1.0-3.2) and 2.2 (95% CI 1.3-3.8), respectively, for a positive TPHA and VDRL test. The results of the test for HbsAg were available in 50 Hlv-positive and 1,028 HIVnegative subjects; the OR of HIV infection in subjects with HbSAg was 3.9 (95% CI 1.7-9.0). Presence or geni tal ulcers at clinical examination was not significantIy associated with the risk of HIV infection (OR yes vs no genital uIcers 1.5, 95% CI 0.6-2.8).
Sexually transmitted diseases and risk of HIV infection.
TESSARI, Gianpaolo;
1996-01-01
Abstract
We have analyzed the association between sexuaUy transmitted diseases (STO) and HIV infection, using data from a crosssectionaI survey of subjects attending STO cIinics in Northern ItaIy conducted since 1988. A totaI of 1,711 subjects (1,259 maIes, 452 females), who had referred themseIves to three STO cIinics in Northern Italy for suspected STO or STO treatment, were included for the study. Out of these, 145 subjects (113 males and 32 females) were Hlv-positìve. A total of 58 mv -positive and 368 mv -negative subjects reported a history of STO; the corresponding odds ratio (OR) was 2.3 (95% confidence interval (CI) 1.5-3.6) for subjects reporting a bistory of STO. Considering various STD in detaiIs, tbe estimated OR was 1.8 (95"1. CI 0.8-3.8) for a bistory of gonorrboea and 1.5 (95% CI 0.8-2.7) of syphilis, and tbe OR was 1.8 (95% CI 1.0-3.2) and 2.2 (95% CI 1.3-3.8), respectively, for a positive TPHA and VDRL test. The results of the test for HbsAg were available in 50 Hlv-positive and 1,028 HIVnegative subjects; the OR of HIV infection in subjects with HbSAg was 3.9 (95% CI 1.7-9.0). Presence or geni tal ulcers at clinical examination was not significantIy associated with the risk of HIV infection (OR yes vs no genital uIcers 1.5, 95% CI 0.6-2.8).
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