CCAAT displacement protein (CDP) is a putative repressor of tissue-specific gene expression (1) implicated in regulation of expression of the human myeloid-specific gene, gp91-phox (9). The cDNA sequence of the human gene (6) predicts a polypeptide of 1506 amino acids, with a homeodomain and three repeated motifs closely homologous to cut, a protein known to specify the cell fate of periferal neurons and other tissues during embryonic development of Drosophila (2).
Regional localization of the CCAAT displacement protein gene (CUTL1) to 7q22 by analysis of somatic cell hybrids.
LIEVENS, Patricia;
1993-01-01
Abstract
CCAAT displacement protein (CDP) is a putative repressor of tissue-specific gene expression (1) implicated in regulation of expression of the human myeloid-specific gene, gp91-phox (9). The cDNA sequence of the human gene (6) predicts a polypeptide of 1506 amino acids, with a homeodomain and three repeated motifs closely homologous to cut, a protein known to specify the cell fate of periferal neurons and other tissues during embryonic development of Drosophila (2).
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