A carbapenem-resistant Klebsiella pneumoniae was isolated from a blood-culture of an inpatient from Libya, hospitalized in the intensive-care unit of Negrar Hospital, Italy. The clinical isolate carried the following β-lactamase genes, blaTEM -1 , blaSHV -11 , blaOXA -1 , blaCTX -M-15 and blaOXA -48 , respectively. The blaOXA -48 gene was inserted in the Tn1999.2 transposon type, carried on a conjugative, 60-kilobase plasmid, that presented an L/M backbone, hosted by a multidrug-resistant ST 101 K. pneumoniae strain. Our report highlights the international transfer of blaOXA -48 gene and the importance of screening measures of multidrug-resistant Enterobacteriaceae.

Klebsiella pneumoniae harbouring OXA-48 carbapenemase in a Libyan refugee in Italy.

KOCSIS, Erika;CORNAGLIA, Giuseppe;MAZZARIOL, Annarita
2013

Abstract

A carbapenem-resistant Klebsiella pneumoniae was isolated from a blood-culture of an inpatient from Libya, hospitalized in the intensive-care unit of Negrar Hospital, Italy. The clinical isolate carried the following β-lactamase genes, blaTEM -1 , blaSHV -11 , blaOXA -1 , blaCTX -M-15 and blaOXA -48 , respectively. The blaOXA -48 gene was inserted in the Tn1999.2 transposon type, carried on a conjugative, 60-kilobase plasmid, that presented an L/M backbone, hosted by a multidrug-resistant ST 101 K. pneumoniae strain. Our report highlights the international transfer of blaOXA -48 gene and the importance of screening measures of multidrug-resistant Enterobacteriaceae.
carbapenem resistance; IncL/M-like plasmid; Klebsiella pneumoniae ST 101; OXA-48; Tn1999.2
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/570950
Citazioni
  • ???jsp.display-item.citation.pmc??? 9
  • Scopus 24
  • ???jsp.display-item.citation.isi??? 25
social impact