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EnglishPURPOSE OF REVIEW: To describe the incidence, major risk factors, and the clinical, electrophysiological, and histological features of critical illness myopathy (CIM). Major pathogenetic mechanisms and long-term consequences of CIM are also reviewed. RECENT FINDINGS: CIM is frequently associated with critical illness polyneuropathy (CIP), and may have a relevant impact on patients' outcome. CIM has an earlier onset than CIP, and recovery is faster. Loss of myosin filaments on muscle biopsy is important to diagnose CIM, and has a good prognosis. Critical illness, use of steroids, and immobility concur in causing CIM. SUMMARY: A rationale diagnostic approach to CIM using clinical, electrophysiological, and muscle biopsy investigations is important to plan adequate therapy and to predict recovery.
Critical illness myopathy. / Latronico N.;Tomelleri G.;Filosto M.. - In: CURRENT OPINION IN RHEUMATOLOGY. - ISSN 1040-8711. - STAMPA. - 24:6(2012), pp. 616-622.
| Titolo: | Critical illness myopathy. |
| Autori: | |
| Data di pubblicazione: | 2012 |
| Rivista: | |
| Citazione: | Critical illness myopathy. / Latronico N.;Tomelleri G.;Filosto M.. - In: CURRENT OPINION IN RHEUMATOLOGY. - ISSN 1040-8711. - STAMPA. - 24:6(2012), pp. 616-622. |
| Abstract: | PURPOSE OF REVIEW: To describe the incidence, major risk factors, and the clinical, electrophysiological, and histological features of critical illness myopathy (CIM). Major pathogenetic mechanisms and long-term consequences of CIM are also reviewed. RECENT FINDINGS: CIM is frequently associated with critical illness polyneuropathy (CIP), and may have a relevant impact on patients' outcome. CIM has an earlier onset than CIP, and recovery is faster. Loss of myosin filaments on muscle biopsy is important to diagnose CIM, and has a good prognosis. Critical illness, use of steroids, and immobility concur in causing CIM. SUMMARY: A rationale diagnostic approach to CIM using clinical, electrophysiological, and muscle biopsy investigations is important to plan adequate therapy and to predict recovery. |
| Handle: | http://hdl.handle.net/11562/451737 |
| Appare nelle tipologie: | 01.01 Articolo in Rivista |
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