Cyclosporine-A is being used increasingly for immunosuppression in patients undergoing organ transplantation. Hepatotoxicity has been noted to occur in up to 20% of renal transplant recipients receiving the drug. The exact nature of this hepato-toxicity, however, has not been defined, although it has been manifested principally, if not exclusively, as elevated serum bilirubin levels. The authors have observed a similar elevation of serum bilirubin levels in cardiac transplant recipients receiving cyclosporine-A and prednisone for immunosuppression.
Titolo: | Cholestasis in heart transplant recipients treated with cyclosporine. |
Autori: | |
Data di pubblicazione: | 1983 |
Rivista: | |
Abstract: | Cyclosporine-A is being used increasingly for immunosuppression in patients undergoing organ transplantation. Hepatotoxicity has been noted to occur in up to 20% of renal transplant recipients receiving the drug. The exact nature of this hepato-toxicity, however, has not been defined, although it has been manifested principally, if not exclusively, as elevated serum bilirubin levels. The authors have observed a similar elevation of serum bilirubin levels in cardiac transplant recipients receiving cyclosporine-A and prednisone for immunosuppression. |
Handle: | http://hdl.handle.net/11562/431658 |
Appare nelle tipologie: | 01.01 Articolo in Rivista |
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