We report the case of a 21-years-old man affected by fluctuating stroke-like symptoms and computed-tomographic hypodensities, associated with seizures, headache, vomiting and a biochemically abnormal response of blood lactate and pyruvate after an oral glucose load. Muscle biopsy showed an increased number of subsarcolemmal mitochondria of increased size. Mitochondrial enzyme analysis was normal. The diagnosis of a MELAS-like mitochondrial disease even with minor muscle involvement is discussed.

Headache, seizures and repente strokes in a young subject: a new case of MELAS-like syndrome?

FABRIZI, Gian Maria;
1988

Abstract

We report the case of a 21-years-old man affected by fluctuating stroke-like symptoms and computed-tomographic hypodensities, associated with seizures, headache, vomiting and a biochemically abnormal response of blood lactate and pyruvate after an oral glucose load. Muscle biopsy showed an increased number of subsarcolemmal mitochondria of increased size. Mitochondrial enzyme analysis was normal. The diagnosis of a MELAS-like mitochondrial disease even with minor muscle involvement is discussed.
Mitochondrial disease; Migraine; strokes; MELAS syndrome
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/429175
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact