Objective: To assess whether second look laparoscopy (LPS) forepithelial ovarian cancer is an acceptable alternative to classicallaparotomy (LPT) in terms of survival and surgical complications.Materials and methods: Forty-nine patients with FIGO stages III/IV ovarian carcinoma with clinical complete response after debulking surgery and platinum-based first line chemotherapy,were included. All patients underwent LPT(n¼28) or LPS(n¼21). A laparoscopic closed technique as previously describedwas employed (Franchi et al, Microlaparoscopy: a new approach tothe reassessment of ovarian cancer patients. Acta Obstet GynecolScand 2000). Surgical data were prospectically collected andcomplications were classified according the French-Italian glossaryof treatment of gynaecological cancers (Chassagne et al, A glossary for reporting complications of treatment in gynaecological cancers. Radiother Oncol 1993).Results: Demographic, clinical characteristics and mean number ofbiopsies were similar between groups. The proportion of patients optimally debulked (<1 cm) [71.4% vs 57.1%, p¼.01], the medianoperative time [120 min (65—210) vs 50 min (30—110), p¼.001], the blood loss [150mL (50—500) vs 50mL (30—150), p¼.001], and the postoperative stay [4 days (2—15) vs 2 days (2—4), p¼.001] were higher in women who underwent LPT than in those who had LPS.No difference was present in the overall and disease free survivalrate between groups (log rank test). No major intraoperative orpostoperative complications were observed. Two patients in theLPT group had wound infection.Conclusions: Second look laparoscopy is an acceptable alternativeto second look laparotomy.
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