We describe a family with autosomal dominant polycystic kidney disease in which molecular typing with closely linked markers for the PKD1 and PKD2 genes indicated absence of linkage. Thus, a third still unknown locus appears likely to be involved in disease development. This is the fourth 'PKD3- linked' family described to date and the first from Italy.

An Italian family with autosomal dominant polycystic kidney disease unlinked to either the PKD1 or PKD2 gene

TURCO, Alberto;PIGNATTI, Pierfranco
1996-01-01

Abstract

We describe a family with autosomal dominant polycystic kidney disease in which molecular typing with closely linked markers for the PKD1 and PKD2 genes indicated absence of linkage. Thus, a third still unknown locus appears likely to be involved in disease development. This is the fourth 'PKD3- linked' family described to date and the first from Italy.
1996
Autosomal dominant polycystic kidney disease; genetic heterogeneity; PKD3 gene;
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/4011
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