Autoimmune pancreatitis (AIP) is a well-defined clinical entitypathologically different from all the other forms of chronic pancreatitis. Since its first description, the concept of the disease has greatly changed over time. On the basis of pathological findings, the disease has been recently classified in type 1 AIP (also called Lympho-Plasmacytic Sclerosing Pancreatitis – LPSP), and type 2 AIP (also called Idiopathic Duct-centric Chronic Pancreatitis – IDCP), as reported by Matsubayashi et al. [1]. These two forms of AIP seem to have different clinical profiles, since type 1 AIP is characterized by other organ involvement (biliary tract, salivary glands, gastrointestinal tract, kidney, retroperitoneum) and frequent relapses after steroid treatment,whereas type 2 AIP seems to be associated with ulcerativecolitis and does not relapse. However, both forms show a goodresponse to steroids.

Serum IgG4 in autoimmune pancreatitis: a marker of disease severity and recurrence?

FRULLONI, Luca;LUNARDI, Claudio
2011

Abstract

Autoimmune pancreatitis (AIP) is a well-defined clinical entitypathologically different from all the other forms of chronic pancreatitis. Since its first description, the concept of the disease has greatly changed over time. On the basis of pathological findings, the disease has been recently classified in type 1 AIP (also called Lympho-Plasmacytic Sclerosing Pancreatitis – LPSP), and type 2 AIP (also called Idiopathic Duct-centric Chronic Pancreatitis – IDCP), as reported by Matsubayashi et al. [1]. These two forms of AIP seem to have different clinical profiles, since type 1 AIP is characterized by other organ involvement (biliary tract, salivary glands, gastrointestinal tract, kidney, retroperitoneum) and frequent relapses after steroid treatment,whereas type 2 AIP seems to be associated with ulcerativecolitis and does not relapse. However, both forms show a goodresponse to steroids.
autoimmune pancreatitis; IgG4; diagnosis; prognosis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/391071
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