NF-kappaB transcription factors and the signaling pathways that activate them play a critical role in cancer development, progression and therapy, and recently have become a focal point for intense drug discovery and development efforts. This article presents a critical review on the different types of inhibitors targeting the NF-kappaB pathway at several stages.

NF-kappa B as a target for cancer therapy.

MELISI, Davide;
2007-01-01

Abstract

NF-kappaB transcription factors and the signaling pathways that activate them play a critical role in cancer development, progression and therapy, and recently have become a focal point for intense drug discovery and development efforts. This article presents a critical review on the different types of inhibitors targeting the NF-kappaB pathway at several stages.
2007
Animals, Antineoplastic Agents; administration /&/ dosage/chemistry, Drug Delivery Systems; methods, Humans, NF-kappa B; antagonists /&/ inhibitors/metabolism, Neoplasms; drug therapy/metabolism, Signal Transduction; drug effects/physiology
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/388924
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