Biocompatible highly bright silica nanoparticles were designed, prepared and tested in small living organisms for both in vivo and ex vivo imaging. The results that we report here demonstrate that they are suitable for optical imaging applications as a possible alternative to commercially available fluorescent materials including quantum dots. Moreover, the tunability of their photophysical properties, which was enhanced by the use of different dyes as doping agents, constitutes a very important added value in the field of medical diagnostics.

Multicolor core/shell silica nanoparticles for in vivo and ex vivo imaging.

BOSCHI, Federico;CALDERAN, Laura;ROSSI, Barbara;BECCHI, Serena;SBARBATI, Andrea
2012

Abstract

Biocompatible highly bright silica nanoparticles were designed, prepared and tested in small living organisms for both in vivo and ex vivo imaging. The results that we report here demonstrate that they are suitable for optical imaging applications as a possible alternative to commercially available fluorescent materials including quantum dots. Moreover, the tunability of their photophysical properties, which was enhanced by the use of different dyes as doping agents, constitutes a very important added value in the field of medical diagnostics.
Biocompatible silica nanoparticles; in vivo imaging; ex vivo imaging
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/381414
Citazioni
  • ???jsp.display-item.citation.pmc??? 14
  • Scopus 48
  • ???jsp.display-item.citation.isi??? 47
social impact