We report 4 PD patients who presented reversible PS induced by rasagiline treatment, introduced to manage mild motor worsening or wearing-off phenomena. Within 4 weeks after rasagiline 1 mg/day introduction, the patients developed PS. Withdrawal of rasagiline led to the rapid improvement of posture within 4 weeks in all cases confirmed by EMG testing in longissimus thoracis muscle. The recognition of reversibility of PS during the initial stages of its appearance may be of considerable clinical importance as it may facilitate the rapid withdrawal or reintroduction of dopaminergic treatment.

Reversible Pisa syndrome in patients with Parkinson's disease on rasagiline therapy.

SQUINTANI, Giovanna;BOMBIERI, Federica;TINAZZI, Michele
2011-01-01

Abstract

We report 4 PD patients who presented reversible PS induced by rasagiline treatment, introduced to manage mild motor worsening or wearing-off phenomena. Within 4 weeks after rasagiline 1 mg/day introduction, the patients developed PS. Withdrawal of rasagiline led to the rapid improvement of posture within 4 weeks in all cases confirmed by EMG testing in longissimus thoracis muscle. The recognition of reversibility of PS during the initial stages of its appearance may be of considerable clinical importance as it may facilitate the rapid withdrawal or reintroduction of dopaminergic treatment.
2011
Pisa syndrome; Parkinson's disease; rasagiline therapy; patient
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/379622
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