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EnglishDuring Gn-RHa plus hGH therapy there was a significant increase in height velocity, in urinary GH levels, in serum IGF-I and IGFBP-3 levels. Bone age did not seem to advance faster than chronological age and this may imply a better prediction in adult height. In our opinion, only in a small percentage of patients affected by precocious puberty (with a very low predicted adult height or an important reduction of growth velocity during Gn-RHa treatment) may an association with hGH therapy be useful.
| Titolo: | Use of combined Gn-RH agonist anf hGH therapy for better attining the goals in precocious puberty treatment |
| Autori: | |
| Data di pubblicazione: | 1995 |
| Rivista: | |
| Abstract: | During Gn-RHa plus hGH therapy there was a significant increase in height velocity, in urinary GH levels, in serum IGF-I and IGFBP-3 levels. Bone age did not seem to advance faster than chronological age and this may imply a better prediction in adult height. In our opinion, only in a small percentage of patients affected by precocious puberty (with a very low predicted adult height or an important reduction of growth velocity during Gn-RHa treatment) may an association with hGH therapy be useful. |
| Handle: | http://hdl.handle.net/11562/360456 |
| Appare nelle tipologie: | 01.01 Articolo in Rivista |
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