The in vivo role of leukocyte function-associated antigen-1 in cytotoxic cell activity against tumors induced by Moloney-murine sarcoma/leukemia retroviral complex.

Rosato, A.; Bronte, Vincenzo; Pollis, F.; Mandruzzato, S.; Zambon, A.; Zanovello, P.; Collavo, D.

The in vivo role of LFA-1 molecule in the immune reaction to a murine retrovirus-induced tumor was investigated. Local and systemic treatment with high doses of anti-LFA-1 monoclonal antibody led to tumor progression by blocking CTL interaction with tumor cells without interfering with CTL generation and localization in the tumor mass.

Titolo:	The in vivo role of leukocyte function-associated antigen-1 in cytotoxic cell activity against tumors induced by Moloney-murine sarcoma/leukemia retroviral complex.
Autori:	A. Rosato Bronte, Vincenzo F. Pollis S. Mandruzzato A. Zambon P. Zanovello D. Collavo mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	1992
Rivista:	LEUKEMIA
Abstract:	The in vivo role of LFA-1 molecule in the immune reaction to a murine retrovirus-induced tumor was investigated. Local and systemic treatment with high doses of anti-LFA-1 monoclonal antibody led to tumor progression by blocking CTL interaction with tumor cells without interfering with CTL generation and localization in the tumor mass.
Handle:	http://hdl.handle.net/11562/360032
Appare nelle tipologie:	01.01 Articolo in Rivista

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