We studied the activation signals of LGL, from LDGL patients, following incubation with susceptible K562 target cells. The findings showed that LGL lysis is independent of [Ca2+]i rise and cytolytic granule exocytosis, and most likely involves alternative, as yet unidentified, mechanisms.
Titolo: | Interaction of large granular lymphocytes with susceptible target does not induce second messenger and cytolytic granule exocytosis. |
Autori: | |
Data di pubblicazione: | 1992 |
Rivista: | |
Abstract: | We studied the activation signals of LGL, from LDGL patients, following incubation with susceptible K562 target cells. The findings showed that LGL lysis is independent of [Ca2+]i rise and cytolytic granule exocytosis, and most likely involves alternative, as yet unidentified, mechanisms. |
Handle: | http://hdl.handle.net/11562/360031 |
Appare nelle tipologie: | 01.01 Articolo in Rivista |
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