CATALOGO DEI PRODOTTI DELLA RICERCA
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EnglishThe aim of this study was to build a predictive model of non-alcoholic fatty liver disease (NAFLD) in obese children. Fifty-six obese 10-year-old children underwent blood tests for biochemical measures and magnetic resonance imaging for NAFLD diagnosis. A model combining waist-to-height ratio, HOMA-IR, adiponectin and ALT was very accurate in predicting NAFLD (AUROC = 0.94[95% C.I.: 0.89-0.99], p < 10). When adiponectin was not included in the model, the discrimination accuracy was still good (AUROC = 0.88[95% C.I.: 0.79-0.97], p < 10). In conclusion, a predictive equation combining routinely available variables may allow physicians to identify obese children at the highest risk of NAFLD.
| Titolo: | Biochemical parameters and anthropometry predict NAFLD in obese children |
| Autori: | |
| Data di pubblicazione: | 2011 |
| Rivista: | |
| Abstract: | The aim of this study was to build a predictive model of non-alcoholic fatty liver disease (NAFLD) in obese children. Fifty-six obese 10-year-old children underwent blood tests for biochemical measures and magnetic resonance imaging for NAFLD diagnosis. A model combining waist-to-height ratio, HOMA-IR, adiponectin and ALT was very accurate in predicting NAFLD (AUROC = 0.94[95% C.I.: 0.89-0.99], p < 10). When adiponectin was not included in the model, the discrimination accuracy was still good (AUROC = 0.88[95% C.I.: 0.79-0.97], p < 10). In conclusion, a predictive equation combining routinely available variables may allow physicians to identify obese children at the highest risk of NAFLD. |
| Handle: | http://hdl.handle.net/11562/356384 |
| Appare nelle tipologie: | 01.01 Articolo in Rivista |
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