In this paper a novel mechanism of DNA recombination is discussed, that turned out to be a good implementation key to develop new procedures for DNA manipulation. It is called XPCR as it is a variant of the polymerase chain reaction (PCR), which was a revolution in molecular biology as a technique for cyclic amplification of DNA segments. A few DNA algorithms are proposed, that were experimentally proven in different contexts, such as mutagenesis, multiple concatenation, gene driven DNA extraction, and generation of DNA libraries, and some related ongoing work is outlined.

Algorithmic Applications of XPCR

FRANCO, Giuditta;MANCA, Vincenzo
2011

Abstract

In this paper a novel mechanism of DNA recombination is discussed, that turned out to be a good implementation key to develop new procedures for DNA manipulation. It is called XPCR as it is a variant of the polymerase chain reaction (PCR), which was a revolution in molecular biology as a technique for cyclic amplification of DNA segments. A few DNA algorithms are proposed, that were experimentally proven in different contexts, such as mutagenesis, multiple concatenation, gene driven DNA extraction, and generation of DNA libraries, and some related ongoing work is outlined.
Algorithmic analysis; DNA extraction; DNA mutagenesis; DNA recombination; PCR; splicing.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/341533
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