Red wine is a widely consumed beverage with multiple beneficial effects on human health. In the present paper, the anticaries properties of red wine were studied in vitro and ex vivo. Our in vitro findings shows that dealcoholised red wine, besides exerting antibacterial activity. strongly interferes with Streptococcus mutans adhesion to saliva-coated hydroxyapatite (sHA) beads. promotes its detachment from sHA, and powerfully inhibits in vitro biofilm formation. The main components responsible for such activities were found to be proanthocyanidins. The ability of red wine to inhibit ex vivo S. mutans biofilm formation on the occlusal surface of natural human teeth also was demonstrated. Our data indicates that protection of the oral cavity from the cariogenic action of S. mutans may be another beneficial effect of the moderate consumption of red wine. (C) 2009 Elsevier Ltd. All rights reserved.

Isolation of red wine components with anti-adhesion and anti-biofilm activity against Streptococcus mutans

SIGNORETTO, Caterina;CANEPARI, Pietro;
2010-01-01

Abstract

Red wine is a widely consumed beverage with multiple beneficial effects on human health. In the present paper, the anticaries properties of red wine were studied in vitro and ex vivo. Our in vitro findings shows that dealcoholised red wine, besides exerting antibacterial activity. strongly interferes with Streptococcus mutans adhesion to saliva-coated hydroxyapatite (sHA) beads. promotes its detachment from sHA, and powerfully inhibits in vitro biofilm formation. The main components responsible for such activities were found to be proanthocyanidins. The ability of red wine to inhibit ex vivo S. mutans biofilm formation on the occlusal surface of natural human teeth also was demonstrated. Our data indicates that protection of the oral cavity from the cariogenic action of S. mutans may be another beneficial effect of the moderate consumption of red wine. (C) 2009 Elsevier Ltd. All rights reserved.
2010
Red wine; Streptococcus mutans; Caries; Adherence; Biofilm
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/338937
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 40
  • ???jsp.display-item.citation.isi??? 28
social impact