We report the allele and genotype frequencies in Italians of eight unlinked commonly utilized polymorphic loci: HUMTHO1, HUMFES/FPS, HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and GC. Genomic DNA from at least 100 individuals was amplified by PCR and typed after electrophoresis (HUMTHO1, HUMFES/FPS), or reverse dot-blot (HLA-DQA1 and the other five loci). The allelic frequencies determined were compared with available population data. These results are useful for population and individual identification studies. © 1995 Academic Press.
Allele and genotype frequencies of eight DNA polymorphisms in the Italian population
TRABETTI, Elisabetta;GALAVOTTI, Roberta;DE LEO, Domenico;PIGNATTI, Pierfranco
1995-01-01
Abstract
We report the allele and genotype frequencies in Italians of eight unlinked commonly utilized polymorphic loci: HUMTHO1, HUMFES/FPS, HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and GC. Genomic DNA from at least 100 individuals was amplified by PCR and typed after electrophoresis (HUMTHO1, HUMFES/FPS), or reverse dot-blot (HLA-DQA1 and the other five loci). The allelic frequencies determined were compared with available population data. These results are useful for population and individual identification studies. © 1995 Academic Press.
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