Objectives: To investigate the relationship between fasting plasma glucose (FPG) and shortened activated partial thromboplastin time (APTT), an independent risk factor for thrombosis. Design and methods: We analyzed outpatients' results of coagulation tests and FPG. Results: When compared with euglycemic subjects, those with impaired fasting glucose and diabetes displayed significantly shortened APTTs. Conclusions: This previously unreported association deserves scrutiny, because APTT is relatively inexpensive and it might identify diabetic patients at major risk of thrombosis. © 2008 The Canadian Society of Clinical Chemists.
Epidemiological association between fasting plasma glucose and shortened APTT
LIPPI, Giuseppe;TARGHER, Giovanni;MONTAGNANA, Martina;SALVAGNO, GIAN LUCA;GUIDI, Giancesare;
2009-01-01
Abstract
Objectives: To investigate the relationship between fasting plasma glucose (FPG) and shortened activated partial thromboplastin time (APTT), an independent risk factor for thrombosis. Design and methods: We analyzed outpatients' results of coagulation tests and FPG. Results: When compared with euglycemic subjects, those with impaired fasting glucose and diabetes displayed significantly shortened APTTs. Conclusions: This previously unreported association deserves scrutiny, because APTT is relatively inexpensive and it might identify diabetic patients at major risk of thrombosis. © 2008 The Canadian Society of Clinical Chemists.
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