Cerebrospinal fluid specimens from 226 patients with suspected viral infections of the central nervous system (CNS) were tested by polymerase chain reaction (PCR) to identify the most frequent viruses involved in these infections. A positive PCR result was obtained in 18 patients (7 cases positive for herpes simplex viruses, 5 for enterovirus, 3 for JC virus, 2 for varicella-zoster virus, and 1 for Epstein-Barr virus). All patients with positive PCR results had a definite diagnosis of CNS viral infection. However, a negative result did not rule out the possibility of viral infection of the CNS.

A two-year prospective study of clinical criteria and polymerase chain reaction assay of cerebrospinal fluid for the diagnosis of viral infections of the central nervous system

BOARETTI, Marzia;SCALET, Giovanna;FONTANA, Roberta
2008-01-01

Abstract

Cerebrospinal fluid specimens from 226 patients with suspected viral infections of the central nervous system (CNS) were tested by polymerase chain reaction (PCR) to identify the most frequent viruses involved in these infections. A positive PCR result was obtained in 18 patients (7 cases positive for herpes simplex viruses, 5 for enterovirus, 3 for JC virus, 2 for varicella-zoster virus, and 1 for Epstein-Barr virus). All patients with positive PCR results had a definite diagnosis of CNS viral infection. However, a negative result did not rule out the possibility of viral infection of the CNS.
2008
polymerase chain reaction; viral infections of central nervous system; cerebrospinal fluid
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/324447
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