Electroencephalography combined with functional magnetic resonance imaging (EEG-fMRI) may be used to identify blood oxygenation level dependent (BOLD) signal changes associated with physiological and pathological EEG event. In this study we used EEG-fMRI to determine the possible correlation between topographical movement-related EEG changes in brain oscillatory activity recorded from EEG electrodes over the scalp and fMRI-BOLD cortical responses in motor areas during finger movement. Thirty-two channels of EEG were recorded in 9 subjects during eyes-open condition inside a 1.5 T magnetic resonance (MR) scanner using a MR-compatible EEG recording system. Off-line MRI artifact subtraction software was applied to obtain continuous EEG data during fMRI acquisition. For EEG data analysis we used the event-related-synchronization/desynchronization (ERS/ERD) approach to investigate where movement-related decreases in alpha and beta power are located. For image statistical analysis we used a general linear model (GLM) approach. There was a significant correlation between the positive-negative ratio of BOLD signal peaks and ERD values in the electrodes over the region of activation. We conclude that combined EEG-fMRI may be used to investigate movement-related oscillations of the human brain inside an MRI scanner and the movement-related changes in the EMG or EEG signals are useful to identify the brain activation sources responsible for BOLD-signal changes.
EEG and fMRI coregistration to investigate the cortical oscillatory activities during finger movement. / Formaggio E; Storti SF; Avesani M; Cerini R; Milanese F; Gasparini A; Acler M; Pozzi Mucelli R; Fiaschi A; Manganotti P. - In: BRAIN TOPOGRAPHY. - ISSN 0896-0267. - STAMPA. - 21:2(2008), pp. 100-111.
Titolo: | EEG and fMRI coregistration to investigate the cortical oscillatory activities during finger movement. |
Autori: | |
Data di pubblicazione: | 2008 |
Rivista: | |
Citazione: | EEG and fMRI coregistration to investigate the cortical oscillatory activities during finger movement. / Formaggio E; Storti SF; Avesani M; Cerini R; Milanese F; Gasparini A; Acler M; Pozzi Mucelli R; Fiaschi A; Manganotti P. - In: BRAIN TOPOGRAPHY. - ISSN 0896-0267. - STAMPA. - 21:2(2008), pp. 100-111. |
Handle: | http://hdl.handle.net/11562/319981 |
Appare nelle tipologie: | 01.01 Articolo in Rivista |