Background: Controversial data are available on the relationship between magnesium metabolism and glucose homeostasis. Methods: We performed a retrospective analysis to retrieve results of serum magnesium and fasting plasma glucose (FPG) tests (7,659 outpatients >35 years old). Results: Subjects with FPG value >7.0 mmol/L were more likely to had hypomagnesemia. The frequency of hypomagnesemia was also significantly higher among those with high FPG values >7.0 mmol/L. In multivariable linear regression analysis, magnesium was significantly associated with FPG only in patients with FPG >7.0 mmol/L. Conclusions: Magnesium metabolism could be implicated in the glucose homeostasis, especially in patients with FPG values suggestive for diabetes.
Relationship between hypomagnesemia and glucose homeostasis.
MONTAGNANA, Martina;LIPPI, Giuseppe;TARGHER, Giovanni;SALVAGNO, GIAN LUCA;GUIDI, Giancesare
2008-01-01
Abstract
Background: Controversial data are available on the relationship between magnesium metabolism and glucose homeostasis. Methods: We performed a retrospective analysis to retrieve results of serum magnesium and fasting plasma glucose (FPG) tests (7,659 outpatients >35 years old). Results: Subjects with FPG value >7.0 mmol/L were more likely to had hypomagnesemia. The frequency of hypomagnesemia was also significantly higher among those with high FPG values >7.0 mmol/L. In multivariable linear regression analysis, magnesium was significantly associated with FPG only in patients with FPG >7.0 mmol/L. Conclusions: Magnesium metabolism could be implicated in the glucose homeostasis, especially in patients with FPG values suggestive for diabetes.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
