Objective: To investigate the relationship between thyroid and kidney function. Design and methods: 13,383 results of serum creatinine and thyroid stimulating hormone (TSH) were retrieved from the database of our Laboratory. Results: When compared with euthyroid subjects, those with TSH < 0.2 mIU/L and > 2.5 mIU/L had increased and decreased estimated glomerular filtration rate (e-GFR), respectively. TSH levels were an independent predictor of e-GFR. Conclusions: A mutual relationship was observed between kidney and thyroid status. © 2008 The Canadian Society of Clinical Chemists.
Relationship between thyroid status and renal function in a general population of unselected outpatients.
LIPPI, Giuseppe;MONTAGNANA, Martina;TARGHER, Giovanni;SALVAGNO, GIAN LUCA;GUIDI, Giancesare
2008-01-01
Abstract
Objective: To investigate the relationship between thyroid and kidney function. Design and methods: 13,383 results of serum creatinine and thyroid stimulating hormone (TSH) were retrieved from the database of our Laboratory. Results: When compared with euthyroid subjects, those with TSH < 0.2 mIU/L and > 2.5 mIU/L had increased and decreased estimated glomerular filtration rate (e-GFR), respectively. TSH levels were an independent predictor of e-GFR. Conclusions: A mutual relationship was observed between kidney and thyroid status. © 2008 The Canadian Society of Clinical Chemists.
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