A Klebsiella pneumoniae strain resistant to third-generation cephalosporins was isolated in the eastern Netherlands. The strain was found to carry a novel extended-spectrum beta-lactamase, namely, SHV-31. The combination of the two mutations by which SHV-31 differs from SHV-1, namely, L35Q and E240K, had previously only been described in association with one or more additional mutations.
Detection of a new SHV-type extended-spectrum ß-lactamase (SHV-31) in a Klebsiella pneumoniae causing a large nosocomial outbreak in the Netherlands
MAZZARIOL, Annarita;KONCAN, RAFFAELLA;CORNAGLIA, Giuseppe
2007-01-01
Abstract
A Klebsiella pneumoniae strain resistant to third-generation cephalosporins was isolated in the eastern Netherlands. The strain was found to carry a novel extended-spectrum beta-lactamase, namely, SHV-31. The combination of the two mutations by which SHV-31 differs from SHV-1, namely, L35Q and E240K, had previously only been described in association with one or more additional mutations.
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