Isolated Presence of Antibody to Hepatitis B core antigen in injection drug users: do they need to be vaccinated?

Quaglio, G.; Lugoboni, F.; Vento, Sandro; Lechi, A.; Accordini, A.; Bossi, C.; Faccini, M.; Mecenero, V.; Pani, A.; Pantalena, M.; Residori, M.; Mezzelani, P.

In a study of 497 injection drug users who had isolated presence of antibody to hepatitis B core antigen (anti-HBc) at the time of enrollment, 404 (81%) retained this condition after a mean of 49 months of follow-up, during which time no new hepatitis B surface antigen marker was detected. These findings support the hypothesis that patients with isolated presence of anti-HBc have strong resistance to reinfection and do not need vaccination.

Titolo:	Isolated Presence of Antibody to Hepatitis B core antigen in injection drug users: do they need to be vaccinated?
Autori:	QUAGLIO G. LUGOBONI F. VENTO, Sandro A. LECHI ACCORDINI A. BOSSI C. FACCINI M. MECENERO V. PANI A. PANTALENA M. RESIDORI M. MEZZELANI P. mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2001
Rivista:	CLINICAL INFECTIOUS DISEASES
Abstract:	In a study of 497 injection drug users who had isolated presence of antibody to hepatitis B core antigen (anti-HBc) at the time of enrollment, 404 (81%) retained this condition after a mean of 49 months of follow-up, during which time no new hepatitis B surface antigen marker was detected. These findings support the hypothesis that patients with isolated presence of anti-HBc have strong resistance to reinfection and do not need vaccination.
Handle:	http://hdl.handle.net/11562/307086
Appare nelle tipologie:	01.01 Articolo in Rivista

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