The case of a nulliparous, 70-year-old woman with long-standing type 2 diabetes mellitus who had regression of the disease during treatment of chronic myeloid leukemia with imatinib, an antineoplastic agent. Type 2 diabetes mellitus was diagnosed when the patient was 62 years of age and weighed 60 kg (body-mass index [the weight in kilograms divided by the square of the height in meters], 24.2) She was treated with diet for one year, oral agents for four years, and insulin thereafter. After the detection of leukocytosis and immature myeloid cells in the blood, chronic myeloid leukemia was diagnosed (in March 2004) and treatment with imatinib (400 mg per day) was initiated. Hematologic remission was documented two months later.
Regression of type 2 diabetes with imatinib?
Veneri, Dino;BONORA, Enzo
2005-01-01
Abstract
The case of a nulliparous, 70-year-old woman with long-standing type 2 diabetes mellitus who had regression of the disease during treatment of chronic myeloid leukemia with imatinib, an antineoplastic agent. Type 2 diabetes mellitus was diagnosed when the patient was 62 years of age and weighed 60 kg (body-mass index [the weight in kilograms divided by the square of the height in meters], 24.2) She was treated with diet for one year, oral agents for four years, and insulin thereafter. After the detection of leukocytosis and immature myeloid cells in the blood, chronic myeloid leukemia was diagnosed (in March 2004) and treatment with imatinib (400 mg per day) was initiated. Hematologic remission was documented two months later.
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