The persistence of minimal residual disease (MRD) following the induction of complete remission (CR) in patients with acute lymphoblastic leukemia (ALL) predicts a poor outcome in childhood, whereas fewer data are so far available in adults. In the present study we investigated MRD in a single center series of 24 adult patients with ALL using a flowcytometric approach based on the detection of leukemia-specific marker combinations.

Flow-cytometric detection of minimal residual disease in adult acute lymphoblastic leukemia

KRAMPERA, Mauro;PERBELLINI, Omar;PIZZOLO, Giovanni
2001-01-01

Abstract

The persistence of minimal residual disease (MRD) following the induction of complete remission (CR) in patients with acute lymphoblastic leukemia (ALL) predicts a poor outcome in childhood, whereas fewer data are so far available in adults. In the present study we investigated MRD in a single center series of 24 adult patients with ALL using a flowcytometric approach based on the detection of leukemia-specific marker combinations.
acute lymphoblastic leukemia; minimal residual disease
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/304284
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