Leptin, a key regulator of body weight, has also been proposed as a regulator of bone mass. This study demonstrates that high serum levels of leptin are predictive of a low risk of nontraumatic fracture. This analysis was not a predefined aim of the original Bruneck Study but a post hoc decision stimulated by the recently emerging data on the role of leptin in bone metabolism.
Serum leptin level and the risk of non-traumatic fracture.
BONORA, Enzo;MUGGEO, Michele;
2004-01-01
Abstract
Leptin, a key regulator of body weight, has also been proposed as a regulator of bone mass. This study demonstrates that high serum levels of leptin are predictive of a low risk of nontraumatic fracture. This analysis was not a predefined aim of the original Bruneck Study but a post hoc decision stimulated by the recently emerging data on the role of leptin in bone metabolism.
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