The Xenon 133 method for the measurement of the cerebral blood flow (CBF) is value in assessing the regional cerebral perfusion and cerebral perfusion reserve in patient with carotid artery occlusive disease (CAOD). The effect of CAOD on CBF has been observed in 3 patients, by measuring the global and regional CBF and cerebral vasoreactivity with acetazolamide test. Most patients presented a decreased cerebral vasoreactivity; 10 patients presented a interhemispheric asimmetry. 16 patients underwent carotid revascularization procedure: carotid endarterectomy (14) or carotid-subclavian by-pass (2). We observed an increased cerebral vasoreactivity in 4 patients and the normalization of the interhemispheric simmetry in 5 patients. We conclude that the measurement of CBF with Xenon 133 method reveals the emodynamic effects of carotid endoarterectomy in intracranial circulation and suggests that this method is valuable in predicting the prognosis in patients with CAOD, although further studies are needed.

Cerebral blood flow evaluation in patient with carotid occlusive disease: Carotid endoarterectomy emodynamic effect on intracranial circulation. [Lo studio del microcircolo cerebrale nei pazienti con patologia ostruttiva carotidea; Valutazione delle modificazioni fisiopatologiche conseguenti all'intervento di tea carotidea].

SCURO, Alberto;TALACCHI, Andrea;POLLINI, Giovanni Paolo
1997

Abstract

The Xenon 133 method for the measurement of the cerebral blood flow (CBF) is value in assessing the regional cerebral perfusion and cerebral perfusion reserve in patient with carotid artery occlusive disease (CAOD). The effect of CAOD on CBF has been observed in 3 patients, by measuring the global and regional CBF and cerebral vasoreactivity with acetazolamide test. Most patients presented a decreased cerebral vasoreactivity; 10 patients presented a interhemispheric asimmetry. 16 patients underwent carotid revascularization procedure: carotid endarterectomy (14) or carotid-subclavian by-pass (2). We observed an increased cerebral vasoreactivity in 4 patients and the normalization of the interhemispheric simmetry in 5 patients. We conclude that the measurement of CBF with Xenon 133 method reveals the emodynamic effects of carotid endoarterectomy in intracranial circulation and suggests that this method is valuable in predicting the prognosis in patients with CAOD, although further studies are needed.
CBF; Cerebrovascular disease; Xenon 133
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/301912
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