PSMA is an integral membrane glycoprotein that is overexpressed in prostate carcinomas rendering this cell surface marker an appropriate target for antibody-vehicled drugs and toxins. Here we report on the biosynthesis, processing and transport of PSMA in COS-1 cells transfected with a human cDNA encoding PSMA.
Prostate-specific membrane antigen (PSMA) associates early in the endoplasmic reticulum with lipid microdomains
CASTELLETTI, Deborah;FRACASSO, Giulio;COLOMBATTI, Marco;
2005-01-01
Abstract
PSMA is an integral membrane glycoprotein that is overexpressed in prostate carcinomas rendering this cell surface marker an appropriate target for antibody-vehicled drugs and toxins. Here we report on the biosynthesis, processing and transport of PSMA in COS-1 cells transfected with a human cDNA encoding PSMA.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
