PSMA is an integral membrane glycoprotein that is overexpressed in prostate carcinomas rendering this cell surface marker an appropriate target for antibody-vehicled drugs and toxins. Here we report on the biosynthesis, processing and transport of PSMA in COS-1 cells transfected with a human cDNA encoding PSMA.

Prostate-specific membrane antigen (PSMA) associates early in the endoplasmic reticulum with lipid microdomains

CASTELLETTI, Deborah;FRACASSO, Giulio;COLOMBATTI, Marco;
2005-01-01

Abstract

PSMA is an integral membrane glycoprotein that is overexpressed in prostate carcinomas rendering this cell surface marker an appropriate target for antibody-vehicled drugs and toxins. Here we report on the biosynthesis, processing and transport of PSMA in COS-1 cells transfected with a human cDNA encoding PSMA.
2005
PSMA; trafficking; prostate
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/29231
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