High prevalence of sustained remission of idiopathic thrombocytopenic purpura after helicobacter pylori eradication

Veneri, D; Krampera, Mauro; Franchini, M.

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We studied the effect of Helicobacter pylori (H. pylori ) eradication in 43 consecutive H. pylori-infected patients with idiopathic thrombocytopenic purpura. H. pylori was eradicated with antibiotics in 41 of them (95.3%). The difference between the mean platelet count before and after therapy was statistically significant (54.3109/l vs. 119.1109/l; P < 0.001). A sustained remission was observed in 20 patients (48.8%), after a median follow-up of 31.2 months. None of the patients still infected by H. pylori after therapy reached normal platelet values. The long-term follow-up confirms the efficacy of H. pylori eradication in H. pylori-infected ITP patients.

Titolo:	High prevalence of sustained remission of idiopathic thrombocytopenic purpura after helicobacter pylori eradication
Autori:	Veneri D KRAMPERA, Mauro Franchini M. mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2005
Rivista:	PLATELETS
Abstract:	We studied the effect of Helicobacter pylori (H. pylori ) eradication in 43 consecutive H. pylori-infected patients with idiopathic thrombocytopenic purpura. H. pylori was eradicated with antibiotics in 41 of them (95.3%). The difference between the mean platelet count before and after therapy was statistically significant (54.3109/l vs. 119.1109/l; P < 0.001). A sustained remission was observed in 20 patients (48.8%), after a median follow-up of 31.2 months. None of the patients still infected by H. pylori after therapy reached normal platelet values. The long-term follow-up confirms the efficacy of H. pylori eradication in H. pylori-infected ITP patients.
Handle:	http://hdl.handle.net/11562/24162
Appare nelle tipologie:	01.01 Articolo in Rivista

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