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EnglishSix healthy male volunteers received 1 week's pretreatment with ranitidine, 150 mg twice daily, and placebo in a double-blind cross-over trial. On the 8th day, each volunteer received 1 g of aspirin in order to study the pharmacokinetics of this nonsteroidal anti-inflammatory drug. The results of this study suggest that ranitidine does not induce clinically significant alterations to the kinetics of a single dose of aspirin in healthy males.
| Titolo: | Effect of ranitidine on the absorption of aspirin |
| Autori: | |
| Data di pubblicazione: | 1987 |
| Rivista: | |
| Abstract: | Six healthy male volunteers received 1 week's pretreatment with ranitidine, 150 mg twice daily, and placebo in a double-blind cross-over trial. On the 8th day, each volunteer received 1 g of aspirin in order to study the pharmacokinetics of this nonsteroidal anti-inflammatory drug. The results of this study suggest that ranitidine does not induce clinically significant alterations to the kinetics of a single dose of aspirin in healthy males. |
| Handle: | http://hdl.handle.net/11562/2406 |
| Appare nelle tipologie: | 01.01 Articolo in Rivista |
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