Autoimmune pancreatitis (AIP) is an unusual type of chronic pancreatitis having an underlying autoimmunity mechanism. Lymphoplasmacytic infiltration and fibrosis on histology, and elevated IgG levels or detected autoantibodies on laboratory data support the concept of AIP. Periductal lymphoplasmacytic infiltration and fibrosis, its preferential occurrence in the pancreatic head, and venulitis characterize autoimmune pancreatitis [1]. AIP should be distinguished from alcoholic chronic pancreatitis because steroid therapy for the former type is effective, morphologic changes are reversible, and pancreatic function can return to normal levels [2]. Difficulties can also arise in differentiating AIP from pancreatic carcinoma.

Autoimmune pancreatitis: instrumental diagnosis

MORANA, Giovanni;FACCIOLI, Niccolò;D'ONOFRIO, Mirko;POZZI MUCELLI, Roberto
2005

Abstract

Autoimmune pancreatitis (AIP) is an unusual type of chronic pancreatitis having an underlying autoimmunity mechanism. Lymphoplasmacytic infiltration and fibrosis on histology, and elevated IgG levels or detected autoantibodies on laboratory data support the concept of AIP. Periductal lymphoplasmacytic infiltration and fibrosis, its preferential occurrence in the pancreatic head, and venulitis characterize autoimmune pancreatitis [1]. AIP should be distinguished from alcoholic chronic pancreatitis because steroid therapy for the former type is effective, morphologic changes are reversible, and pancreatic function can return to normal levels [2]. Difficulties can also arise in differentiating AIP from pancreatic carcinoma.
Autoimmune pancreatitis; diagnosis; radiology
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/21895
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