Selective decontamination of the gastrointestinal tract may decrease theincidence of infections due to Gram-negative bacteria or cocci in patients withgranulocytopaenia or with severely impaired host defences (1) . Different selectivedecontamination regimens have been proposed (2, 3) . The possible effects of interferencebetween the immunosuppressive treatment and the antimicrobial chemotherapy on theintestinal microflora were studied in an experimental animal model (rat) .
Immunosuppression and antimicrobial drugs: effects on rats intestinal microflora.
BERTAZZONI MINELLI, Elisa;BENINI, Anna;
1992-01-01
Abstract
Selective decontamination of the gastrointestinal tract may decrease theincidence of infections due to Gram-negative bacteria or cocci in patients withgranulocytopaenia or with severely impaired host defences (1) . Different selectivedecontamination regimens have been proposed (2, 3) . The possible effects of interferencebetween the immunosuppressive treatment and the antimicrobial chemotherapy on theintestinal microflora were studied in an experimental animal model (rat) .
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