Eosinophilic cystitis: Description of two cases and literature review

Eosinophilic cystitis is a rare inflammatory disease of the bladder of unknown etiology and immunologic pathogenesis. We report two cases of eosinophilic cystitis recently observed in adult male patients with negative history for allergic disease and absence of peripheral eosinophilia. The clinical and radiological picture of the illness is not specific and the diagnosis is exclusively histological. In cases which are less severe and of recent origin medical treatment with steroids, antihistamines and/or nonsteroidal antiinflammatory drugs is indicated. However, the most serious and long-standing cases usually require endoscopic or surgical treatment. The endoscopic fulguration of the areas of bladder mucosa affected by eosinophilic cystitis was effective in both our cases.