Relative to chapter: Modulation of CAB39L and SESN1 impinged on clonogenicity and invasiveness of breast cancer cells. We have evaluated the consequences of metformin-miR-21-5p modulation of CAB39L and SESN1 on the clonogenic activity of SUM159PT triplenegative breast cancer cell line (Fig. 4g and Supplementary Fig. S4e). During the generation of the representative images in Fig. 4g (and therefore Supplementary Fig. S4e which is the same experiment), the cell colony staining images from Fig. 2h, 0.5 and 1 nM miR-21-5p inhibitor treatments were inadvertently copied and pasted to represent the metformin + shCAB39L(A) and metformin + siSESN1 treatment conditions of Fig. 4g, respectively. The incorrect images in Fig. 4g and Supplementary Fig. S4e have been replaced by the images from the correct treatment groups. This change does not impact the results because the data with their statistical significance described in the manuscript are based on the correct colony staining images for the assigned treatments.

Correction to: Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities (Cell Discovery, (2017), 3, 1, (17022), 10.1038/celldisc.2017.22)

Milella, M.;Strano, S.;
2024-01-01

Abstract

Relative to chapter: Modulation of CAB39L and SESN1 impinged on clonogenicity and invasiveness of breast cancer cells. We have evaluated the consequences of metformin-miR-21-5p modulation of CAB39L and SESN1 on the clonogenic activity of SUM159PT triplenegative breast cancer cell line (Fig. 4g and Supplementary Fig. S4e). During the generation of the representative images in Fig. 4g (and therefore Supplementary Fig. S4e which is the same experiment), the cell colony staining images from Fig. 2h, 0.5 and 1 nM miR-21-5p inhibitor treatments were inadvertently copied and pasted to represent the metformin + shCAB39L(A) and metformin + siSESN1 treatment conditions of Fig. 4g, respectively. The incorrect images in Fig. 4g and Supplementary Fig. S4e have been replaced by the images from the correct treatment groups. This change does not impact the results because the data with their statistical significance described in the manuscript are based on the correct colony staining images for the assigned treatments.
2024
microRNA 21-5p
CAB39L
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1203449
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