Patients with spinal cord injury (SCI) frequently develop chronic wounds in paralyzed limbs, underscoring the importance of neural regulation and peripheral nerve integrity for tissue repair; however, it remains unclear how concomitant SCI alters the distal responses to peripheral nerve injury (PNI) and the associated microRNA (miRNA) profile.
Spinal cord transverse section hinders Wallerian degeneration and neoangiogenesis after peripheral nerve transection: Involvement of Schwann cells' miR-134–5p
Armato, Ubaldo;Chiarini, Anna;Prà, Ilaria Dal;De Santis, Daniele;Wei, Zairong
2026-01-01
Abstract
Patients with spinal cord injury (SCI) frequently develop chronic wounds in paralyzed limbs, underscoring the importance of neural regulation and peripheral nerve integrity for tissue repair; however, it remains unclear how concomitant SCI alters the distal responses to peripheral nerve injury (PNI) and the associated microRNA (miRNA) profile.
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