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Cirrhosis; Cohort study; Hepatitis C virus; Human immunodeficiency virus; Incidence

Incidence and progression to cirrhosis of new hepatitis C virus infections in persons living with human immunodeficiency virus

ROSSOTTI R;
2017-01-01

Abstract

Cirrhosis; Cohort study; Hepatitis C virus; Human immunodeficiency virus; Incidence
2017
Objective To estimate the incidence of hepatitis C virus (HCV) seroconversion and the risk of severe fibrosis/cirrhosis in HCV seroconverters among persons with human immunodeficiency virus (HIV) infection. Methods We analysed data on 4059 persons with HIV enrolled in a cohort study in Italy. Results Incidence rate of seroconversion was 0.6/100 person-years overall, and drug users and men-who-have-sex-with-men were at highest risk. The cumulative risk of progression to severe fibrosis/cirrhosis was 30% by 10 years after seroconversion. Conclusions New HCV infections have a rapidly progressive course in this population. Persons with HIV and HCV superinfection should be prioritized for treatment with anti-HCV direct-acting antivirals
01.01 Articolo in Rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1189711
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