Did you know that there are thousands of ways to build a connectome from diffusion MRI tractography, and the choice of approach can hugely impact the final connectome and results? To name only a few: Tractography type: deterministic or probabilistic? Parcellation resolution: coarse or fine atlas? Edge weighting: streamline count, length, or microstructural properties? These choices give rise to a daunting garden of forking paths. In this article, we revise fundamental decisions you must make when planning to build a tractography-based connectome and their impact on its network analysis.
A thousand ways to tailor your tractography-based connectome
Daducci, Alessandro;
2025-01-01
Abstract
Did you know that there are thousands of ways to build a connectome from diffusion MRI tractography, and the choice of approach can hugely impact the final connectome and results? To name only a few: Tractography type: deterministic or probabilistic? Parcellation resolution: coarse or fine atlas? Edge weighting: streamline count, length, or microstructural properties? These choices give rise to a daunting garden of forking paths. In this article, we revise fundamental decisions you must make when planning to build a tractography-based connectome and their impact on its network analysis.
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