A biallelic G/T polymorphism within the first intron of COL1A1 gene at a recognition siter for the transcription factor Sp1 has been shown to be significantly related to bone mass and osteoporotic fractures. We have designed a rapid and efficient genotyping method based on allele-specific polymerase chain reaction (ASPCR)
Rapid and efficient genotype analysis of the COL1A1 Sp1 binding site dimorphism, a genetic marker for bone mineral density
SANGALLI, Antonella;MOTTES, Monica
2002-01-01
Abstract
A biallelic G/T polymorphism within the first intron of COL1A1 gene at a recognition siter for the transcription factor Sp1 has been shown to be significantly related to bone mass and osteoporotic fractures. We have designed a rapid and efficient genotyping method based on allele-specific polymerase chain reaction (ASPCR)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
