A biallelic G/T polymorphism within the first intron of COL1A1 gene at a recognition siter for the transcription factor Sp1 has been shown to be significantly related to bone mass and osteoporotic fractures. We have designed a rapid and efficient genotyping method based on allele-specific polymerase chain reaction (ASPCR)
Titolo: | Rapid and efficient genotype analysis of the COL1A1 Sp1 binding site dimorphism, a genetic marker for bone mineral density |
Autori: | |
Data di pubblicazione: | 2002 |
Rivista: | |
Abstract: | A biallelic G/T polymorphism within the first intron of COL1A1 gene at a recognition siter for the transcription factor Sp1 has been shown to be significantly related to bone mass and osteoporotic fractures. We have designed a rapid and efficient genotyping method based on allele-specific polymerase chain reaction (ASPCR) |
Handle: | http://hdl.handle.net/11562/11731 |
Appare nelle tipologie: | 01.01 Articolo in Rivista |
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